Alison,
PANDAS is definitely associated with inflammation mostly in the basal ganglia area which Ibuprofen can help with.
The worsening on Biocidin could be die-off or just an intolerance to the ingredients in the product. It is hard to know since there are so many ingredients in the product.
What I would do for the antimicrobial component is give individual botanicals:
-Berberine
-Uva Ursi
-Grapefruit Seed Extact
-Allicin
-Etc. – chose about 4 to 5 remedies to try. New Beginnings has a good list of liquid botanicals as individual products. Pick one and try for 48 hours. Then add a second, third, etc. as tolerated.
Ibuprofen is great for inflammation, but I agree can be a problem long-term. Check out NeuroProtek from Alognot – https://algonot.com/product/neuroprotek/. Great product. May need to still use Ibuprofen for another week or so and transition over to NeuroProtek.
I hope this helps.
Dr. Woeller