Low levels of pyroglutamic acid on OAT
- This topic has 3 replies, 2 voices, and was last updated 7 years, 9 months ago by
.
-
Posts
-
Dr. Woeller,
I have an 11 year old boy m/c is seizures. What is your experience with a low level of pyroglutamic acid? OAT also reveals elevated arabinose, low dopamine and noradrenaline/adrenaline and nutrient deficiencies as well.
Much appreciated,
LYnnLynn,
A low pyroglutamic doesn’t have clinical significance from my understanding. It’s when the pyroglutamic is high that it indicates a glutathione deficiency.The high arabinose is a problem related to invasive candida. The low HVA can occur from a polypmorphism in Catechol-0-methyltransferase (COMT). Also, low VMA can occur from COMT polymorphism as well.
Dopamine Beta-Hydroxylase (DBH) is the enzyme that converts Dopamine to Norepinephrine. It requires Vitamin C and Copper as a cofactor for activation. However, a polymorphism in DBH commonly causes high dopamine and high HVA.
What kinds of biomedical interventions have been tried?
Dr. Woeller
Dr. Woeller,
This is a new client and will be making dietary and supplement recommendations. Interesting information about the low HVA and low VMA from COMT. I see ALOT of this type of result with children that I work with. I’ve now tested over a dozen children that began with healthy development, then later in development (around age 3 or 4) develop retractable seizures. (30% of children don’t respond to medications). All of these OATs have revealed minimally elevated levels of arabinose (added infections in a few cases) AND low HVA and VMA. I appreciate the reinforcement on the co-factors which I implement in phase I of recommendations and I look forward to learning more about the COMT polymorphism.
Lynn
Lynn,
Great Plains is incorporating polymorphism lectures to their OAT seminars that I do. Starting next month in San Jose they are adding a day two seminar on chemical toxicity and SNP’s from their SNP1000 profile. I am excited to see who this information expand our knowledge with regards to how the OAT is used in clinical practice.Sincerely,
Dr. Woeller
- You must be logged in to reply to this topic.